Sibling Psychiatric Disorders and Risk of Postpartum Psychosis.

ABSTRACT:

Objective

Postpartum psychosis affects 1-2 per 1,000 women following childbirth. Although bipolar disorder and prior postpartum psychosis are established risk factors, the contribution of familial psychiatric history is not well characterized.

Methods

Using Swedish national registers, we identified 1,213,829 women with a full sibling who delivered their first liveborn child between 1980 and 2017. Postpartum psychosis was defined as mania, psychosis, or psychotic depression within 90 days postpartum. Associations between sibling psychiatric diagnoses and postpartum psychosis were estimated using logistic regression with cluster-robust standard errors, including stratification by the woman's own psychiatric history.

Outcomes

Overall, 1,831 women developed postpartum psy

SUBMITTER: Smout S 

PROVIDER: S-EPMC12668109 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature