The carbon isotope ratio of alanine is a biomarker of added sugar and sugar-sweetened beverage intakes: a pooled analysis of 4 studies.

ABSTRACT:

Background

The alanine carbon isotope ratio (CIR) biomarker was positively associated with added sugar (AS) and sugar-sweetened beverage (SSB) intakes in multiple studies from the United States. Association strengths varied, and Ala CIR also correlated with protein source in certain studies.

Objectives

This study examined Ala CIR associations with AS and SSB intakes and animal protein ratio (APR; animal protein/total protein), and adjustment for APR, by pooling data from 4 previous studies.

Methods

We pooled diet and biomarker data from 4 studies (n = 346). These included a cross-sectional study of Yup'ik Alaska Native adults (n = 62), a 12-wk randomized controlled feeding study in males (n = 32), a 2-wk habitual intake controlled feeding study in postmenopausal femal

SUBMITTER: Johnson JJ 

PROVIDER: S-EPMC12668467 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature