Novel Insights into Epiploic Appendagitis in a Breast Cancer Patient on Abemaciclib: A Case Report.

ABSTRACT:

Introduction

Epiploic appendagitis is an uncommon cause of acute abdominal pain, often mimicking surgical emergencies. This case highlights the diagnostic process for epiploic appendagitis in a breast cancer patient receiving abemaciclib, a CDK4/6 (cyclin-dependent kinase) inhibitor, and discusses potential associations with targeted therapies.

Case presentation

We present a case of a 48-year-old female on adjuvant abemaciclib for stage IIIA breast cancer who developed acute left iliac fossa pain. Clinical assessment, laboratory investigations, transvaginal ultrasound, and subsequent computed tomography (CT) imaging of the abdomen and pelvis were performed to establish the diagnosis. CT imaging revealed a characteristic ovoid fat-density lesion with surrounding inflammation

SUBMITTER: Islam J 

PROVIDER: S-EPMC12668706 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature