Placental pathology and its association with duration of abnormal fetal heart tracing in near-term and term infants with hypoxic-ischemic encephalopathy: A retrospective study.

ABSTRACT:

Introduction

Specific fetal heart rate (FHR) patterns are associated with fetal compromise. Several placental histopathological findings are associated with neonatal morbidity and adverse neurodevelopment. The relationships between intrapartum FHR patterns and placental histopathology in infants with hypoxic-ischemic encephalopathy (HIE) remain uncertain. This study hypothesized that in infants with HIE, placental histopathology findings are related to abnormal FHR patterns.

Material and methods

This was an observational study performed on a historical cohort from a single tertiary neonatal intensive care unit. Infants were born at ≥36 weeks' gestation with moderate or severe HIE between September 2006 and December 2021. Placental histopathology was assessed by a perinatal p

SUBMITTER: Fox A 

PROVIDER: S-EPMC12668807 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature