Postpartum hemorrhage after SARS-CoV-2 infection in pregnancy: A Scandinavian register-based cohort study.

ABSTRACT:

Introduction

The aim was to evaluate whether SARS-CoV-2 infection during pregnancy was associated with severe postpartum hemorrhage (PPH), as SARS-CoV-2 infection has been shown to affect the coagulation system.

Material and methods

In this national register-based cohort study in Sweden, Denmark, and Norway, we studied the association between severe PPH according to a registered positive test for SARS-CoV-2 during pregnancy between March 1, 2020 and March 31, 2023 using logistic regression analyses to estimate odds ratios (ORs) with 95% confidence intervals (CI). Country-specific estimates of association were combined in random effects meta-analyses. The primary outcome was severe PPH, defined as a blood loss >1500 mL and/or receiving a blood transfusion.

Results

We i

SUBMITTER: Rasmussen TD 

PROVIDER: S-EPMC12668808 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature