Predicting spontaneous preterm birth with cervical length and fetal fibronectin for symptomatic women of threatened preterm labor: A prospective study.

ABSTRACT:

Introduction

The aim of this study was to assess the effectiveness of fetal fibronectin (fFN) in combination with cervical length for predicting spontaneous preterm birth (sPTB) in women presenting with threatened preterm labor.

Material and methods

This was a prospective study involving singleton pregnancies at 20-36 weeks of gestation with symptoms of threatened preterm labor. Upon admission, cervical length (CL) and fFN test in cervicovaginal secretions were measured. Logistic regression analysis was performed to develop the following models: CL alone, fFN at various thresholds, and their combined models for the prediction of sPTB. Area under the receiver operating characteristic curve (AUROC) was calculated.

Results

A total of 398 cases were analyzed. The median g

SUBMITTER: Fung JCY 

PROVIDER: S-EPMC12668809 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature