Childbearing in women diagnosed with cancer during reproductive age.

ABSTRACT:

Introduction

Fertility after cancer represents a growing clinical concern. This study assessed childbearing outcomes among women diagnosed with cancer during reproductive age between 2012 and 2017 in Lombardy, the largest region in Italy.

Material and methods

Women aged 15-45 years with a primary diagnosis of cancer recorded in hospital discharge records from regional healthcare databases were selected. Each woman diagnosed with cancer was matched with up to five cancer-free women of the same age at diagnosis. The cumulative probability of childbirth up to December 31, 2022 was estimated using the Kalbfleisch-Prentice cumulative incidence function estimator. Cox regression models were used to estimate the cause-specific hazard ratios (HRs) and the 95% confidence intervals (C

SUBMITTER: Esposito G 

PROVIDER: S-EPMC12668817 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature