A Simplified Frailty Measure Improves Risk Stratification in Patients Undergoing Percutaneous Mitral Valve Repair.

ABSTRACT:

Objective

The aim of this study was to examine frailty measures for risk prediction in patients undergoing percutaneous mitral valve repair (PMVR).

Background

Performance of current risk prediction models based on organ morbidity is only moderate.

Methods

The frailty domains exhaustion, slowness, inactivity, weakness, and unintentional weight loss were prospectively assessed in patients undergoing PMVR. The association with mortality and heart failure hospitalization (HFH) during a median follow-up of 506 days was examined and relevant domains were assessed for additive predictive performance over the MitraScore.

Results

Five hundred twenty-four patients were included in the study (mean age [SD]: 77 (9) years, 54.6% male). The risk of mortality and mortality/HF

SUBMITTER: Metze C 

PROVIDER: S-EPMC12668899 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature