Automated ITSS extraction combined with R2* values obtained from enhanced T2*-weighted angiography in magnetic resonance imaging: a promising approach for differentiate cervical adenocarcinoma from squamous carcinoma.

ABSTRACT:

Purpose

This study aims to evaluate the efficacy of utilizing automated intertumoral susceptibility signal (ITSS) intensity extraction combined with R2* values derived from enhanced T2*-weighted angiography (ESWAN) in magnetic resonance imaging (MRI) to distinguish between cervical adenocarcinoma (CA) and cervical squamous carcinoma (CSC).

Methods

Seventy-eight patients who underwent ESWAN from 2014 to 2019 were stratified into two groups: CA (26 patients) and CSC (52 patients). R2* values of the lesions were measured, and ITSS ratios were automatically calculated using the Anatomy Sketch (AS) software. Independent samples t-tests or Mann-Whitney U-tests were utilized to evaluate disparities in the parameters. Binary logistic regression was conducted to identify independent

SUBMITTER: Chen A 

PROVIDER: S-EPMC12668948 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature