Association between preoperative platelet count and transjugular intrahepatic portosystemic shunt procedure-related hemorrhage in cirrhotic patients: a retrospective study.

ABSTRACT:

Objective

Transjugular intrahepatic portosystemic shunt (TIPS) is a high-bleeding-risk vascular intervention. The association between TIPS-related hemorrhage and preprocedural platelet (PLT) count remains unclear.

Methods

This was a retrospective cohort study including patients receiving TIPS procedures for complications related to portal hypertension due to liver cirrhosis between 2011 and 2022. Logistic regression and subgroup analyses were performed to evaluate the relationship between TIPS-related hemorrhage and preprocedural PLT count. Patients were divided into two groups based on a PLT threshold of 50 × 10⁹/L. Furthermore, patients with PLT count < 50 × 10⁹/L were stratified into two subgroups based on a threshold of 20 × 10⁹/L. The pr

SUBMITTER: Li Y 

PROVIDER: S-EPMC12669100 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature