Alterations in resting-state brain connectivity in patients with cervical spondylotic myelopathy: an fNIRS study.

ABSTRACT:

Purpose

This study aimed to investigate the alterations in resting-state functional connectivity (rsFC) in patients with cervical spondylotic myelopathy (CSM) using functional near-infrared spectroscopy (fNIRS), and to explore the neuropathological mechanisms underlying these changes.

Methods

Fifteen CSM patients (JOA score: 12.3 ± 2.1) and 15 age-matched healthy controls (HCs) underwent fNIRS recording during an eyes-open resting state. Hemodynamic signals were acquired from 63 channels covering the prefrontal, parietal, and occipital cortices. Pearson correlation coefficients were calculated for channel-wise time series, and group differences in FC matrices were compared using two-sample t-tests (p < 0.05) with false discovery rate (FDR) correction.

Results

CSM pati

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC12669267 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature