The use of tramadol for cancer-associated pain-a systematic review.

ABSTRACT:

Background

Tramadol has been used for cancer pain and reported in the literature with varying relative effects compared to other analgesics. To our knowledge, there is no comprehensive systematic review documenting the efficacy/effectiveness and safety of tramadol for cancer-associated pain. The aim of this review is to report on the efficacy/effectiveness and safety of tramadol for cancer-associated pain.

Methods

Ovid MEDLINE, Embase, and Cochrane CENTRAL were searched through September 29, 2023. Articles were included if they reported on tramadol in a multi-arm comparative trial, employing either a randomized controlled trial design or an observational study design with a multivariable or propensity-score matched analysis, and reported on efficacy or safety data pertaining

SUBMITTER: Garlapati S 

PROVIDER: S-EPMC12669292 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature