Combined pathological, microbiological and virological evaluation of vitreous aspirates: a retrospective evaluation of 374 vitrectomy specimens with non-neoplastic disorders.

ABSTRACT:

Background

Intraocular infections pose substantial diagnostic challenges due to their varied aetiologies and complex inflammatory responses. The value of combining cytological, microbiological and virological assessments remains underexplored. This extensive retrospective study conducted at a German tertiary care university hospital aims to elucidate the correlation between different inflammatory patterns and detected pathogens in vitreous fluid samples.

Methods

A retrospective analysis of 374 non-neoplastic vitreous samples from 353 patients was performed, integrating cytological, microbiological and virological data with final clinical diagnoses.

Results

Cytological analysis showed 284 instances of lymphocytic uveitis and 76 of granulocytic endophthalmitis. Pathogen

SUBMITTER: Sulyok M 

PROVIDER: S-EPMC12669569 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature