The risk of basal and squamous cell carcinomas of the skin cancer incidence and external radiation in the updated National Registry for radiation workers cohort in the UK.

ABSTRACT: This study presents the most comprehensive evaluation to date of non-melanoma skin cancer (NMSC) risk in the UK National Registry for Radiation Workers, examining separately both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The cohort includes 172,452 workers with over 5.3 million person-years of follow-up (1955-2011) and a mean cumulative dose of 24.9 mSv. Cumulative external radiation was assessed using the personal dose equivalent Hp(10), and Poisson regression estimates the excess relative risk per Sievert (ERR/Sv) of skin cancer incidence. A total of 5748 NMSC cases were identified (4288 BCC, 818 SCC). BCC showed good evidence of a linear dose-response (ERR/Sv = 0.85, 95% CI: 0.39-1.39; p <.001), but this weakened after adjusting for anatomical location as a proxy for

SUBMITTER: Hunter N 

PROVIDER: S-EPMC12670341 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature