Regulating the Assembly of γ-Cyclodextrin Host and Polyoxometalate-Based Guests toward Light-Responsive Hybrid Rotaxanes.

ABSTRACT: The rational design of hybrid organic-inorganic rotaxanes is crucial for advancing molecular machines and functional nanomaterials, yet the integration of metal-oxo clusters into interlocked systems remains challenging. Herein, we present a precision synthesis strategy for hybrid rotaxanes combining γ-cyclodextrin (γ-CD) hosts with Anderson-type polyoxometalate (POM)-based guests. This approach utilizes covalent POM modification coupled with strategically anchored organic functionalities to control supramolecular assembly, enabling the construction of pseudo-[2]-, [3]-, and [4]rotaxanes with controlled structural variations. Significantly, we achieved the first single-crystal examples of supramolecular pseudo-[4]rotaxanes featuring γ-CD dimers threaded by two organo-POM units

SUBMITTER: Chen WJ 

PROVIDER: S-EPMC12670418 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature