Night work during pregnancy and risk of cryptorchidism among male offspring: A Danish nationwide register-based cohort study.

ABSTRACT:

Aim

The aim was to investigate the association between night work during pregnancy and the risk of having a male offspring with cryptorchidism. Furthermore, we explored if the risk of cryptorchidism increased based on trimester-specific night work (gestational weeks 1-12 and 13-22) by sensitivity analyses.

Methods

This register-based cohort study was based on detailed objective working hour data for all employees in the five Danish regions (primarily hospital employees) between 2007 and 2015, retrieved from the Danish Working Hour Database (DWDH). Information on pregnancies and covariates was identified by linking DWDH with the Danish Medical Birth Register. Diagnoses of cryptorchidism were obtained from the Danish National Patient Register. We used logistic regression to in

SUBMITTER: Bertelsen C 

PROVIDER: S-EPMC12670478 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature