Recommendations for Human Sperm Morphology Assessment in 2025: An Expert Review From the French BLEFCO Group.

ABSTRACT:

Background

Numerous publications have questioned the lack of analytical reliability and clinical relevance of sperm morphology assessment for infertility workup and before use of assisted reproductive techniques (ART). There is a huge variability in the performance and interpretation of this test. It has become necessary to evaluate its true medical service rendered to the patient.

Objectives

To develop clinical guidelines for use of spermatozoa morphology assessment during male fertility check-up and before ART.

Materials and methods

These guidelines were produced following a pre-defined standard methodology for narrative and Patient Intervention Comparison Outcomes (PICO) questions. The French Working Group (WG) on Sperm Morphology Assessment consisted of 15 members

SUBMITTER: Gatimel N 

PROVIDER: S-EPMC12670483 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature