Gender Differences in Patients with Advanced Heart Failure: A Secondary Data Analysis of the ENABLE CHF-PC Randomized Clinical Trial.

ABSTRACT:

Background

Women appear to be underrepresented in heart failure and palliative care research. Given this underrepresentation, their unique characteristics, needs, and outcomes require further investigation.

Methods

A secondary analysis of baseline data of the Educate, Nurture, Advise, Before Life Ends Comprehensive Heartcare for Patients and Caregivers study, a randomized clinical trial of Deep South patients ≥50 years of age with advanced HF. Differences in sociodemographics and measures of quality of life and mood between female and male patients were examined using bivariate tests and effect-size measures.

Results

Statistically significant gender differences were observed with females reporting poorer quality of life-The Kansas City Cardiomyopathy Measure (49.55 ± 

SUBMITTER: Aaron-Wade L 

PROVIDER: S-EPMC12670693 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature