Neuroimaging insights into transgender and gender nonconfirming youth: a scoping review.

ABSTRACT:

Background

Gender incongruence in adolescents is a relevant condition in which the gender identity of a person does not correspond with the birth-assigned sex. Individuals with gender dysphoria can experience a distressing burden. The etiology seems to be predominantly biological, but only a few neurobiological correlates have been identified and are not yet embedded in a broader context. The aim of this review is to present an overview about the current state of the literature regarding MRI brain findings in adolescents < 22 years of age with GD/GI also including non-binary identifying adolescents < 22 years. Findings will be discussed considering (a) sample characteristics, (b) the status of possible hormonal therapy including puberty blockers and (c) non-binary identifying perso

SUBMITTER: Bonnekoh LM 

PROVIDER: S-EPMC12670818 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature