Disease burden of chronic hepatitis B and C patients in South Korea: a population-based 16-year cohort study.

ABSTRACT:

Background

The prevalence of chronic hepatitis B (CHB) and C viruses (CHC) has been studied widely, but the burden of CHB and CHC coinfection (CHB/CHC) remains to be elucidated. This study investigated the 16-year trend in the disease burden in patients with CHB and/or CHC.

Methods

This analysis used a customized database from 2002 to 2020 obtained from the Korean National Health Insurance Service. Prevalence of CHB/CHC in patients with CHB and/or CHC was analyzed for each year, sex, and type of healthcare providers. Development of cirrhosis and hepatocellular carcinoma (HCC), and overall survival were evaluated.

Results

A total of 747,476 patients (male: 53.5%) were divided into three groups: CHB (593,962; 79.5%), CHC (129,049; 17.3%), and CHB/CHC (24,465; 3.3%). Reg

SUBMITTER: Jeong O 

PROVIDER: S-EPMC12670844 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature