Coronary Artery Disease and Intradialytic Myocardial Ischemia in Hemodialysis: An Exploratory Study Using Intradialytic Imaging.

ABSTRACT:

Rationale & objective

Recurrent segmental myocardial ischemia (myocardial stunning) is a well-recognized consequence of hemodialysis leading to fixed contractile deficits and increased morbidity and cardiac mortality. Although epicardial coronary artery disease (CAD) is not a prerequisite, hemodialysis patients commonly have significant arterial plaque burden, and the interaction with established CAD and hemodialysis-induced myocardial ischemic injury is currently unknown.

Study design

A single-center cross-sectional study.

Setting & participants

Thirteen patients on maintenance hemodialysis (London, Ontario, and Canada).

Exposure

The presence of significant coronary stenoses as assessed using coronary computed tomography (CT) angiography.

Outcomes

Princ

SUBMITTER: Hur L 

PROVIDER: S-EPMC12671370 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature