The strain-8 study: a multimodal scan-rescan assessment of myocardial strain repeatability.

ABSTRACT:

Aims

Myocardial strain is a powerful, non-invasive diagnostic and prognostic marker in patients with heart disease. However, its applicability is hindered by uncertain repeatability, particularly for segmental values. This study measures the repeatability of myocardial strain across eight imaging methods.

Methods and results

In this prospective study, 20 healthy volunteers (aged 34 ± 8, 14 men) were recruited and scanned twice with eight strain imaging protocols: cardiac magnetic resonance (CMR) at 1.5T and 3T with cine, tagging, and displacement encoding with stimulated echoes (DENSE) sequences, and 2D and 3D echocardiography (Echo). Global and segmental strains were quantified from each scan. Inter-scan repeatability was assessed with the coefficient of variation (CoV), in

SUBMITTER: Bell A 

PROVIDER: S-EPMC12671395 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature