Mortality Trends in Atrial Fibrillation With Cardiomyopathy Among Patients Aged 25 and Older in the United States.

ABSTRACT:

Background

Atrial fibrillation (AF) is a prevalent arrhythmia that frequently coexists with cardiomyopathy, leading to deteriorated cardiovascular outcomes. Analyzing the trends associated with these conditions is essential for improving prevention strategies and management practices.

Methods

CDC WONDER (1999-2023) data were analyzed to assess AF with cardiomyopathy-related mortality in patients aged ≥ 25. Using Joinpoint regression analysis, we calculated age-adjusted mortality rates (AAMRs) per 100,000 patients and average annual percentage changes (AAPCs) to analyze mortality trends.

Results

AF with cardiomyopathy is responsible for 126,377 deaths among adults aged 25 and older. Alarmingly, AAMRs have surged from 1.8 per 100,000 in 1999 to 3.0 in 2023 (AAPC: 2.11,

SUBMITTER: Naveed MA 

PROVIDER: S-EPMC12671472 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature