Racial and sex disparities in inpatient outcomes of patients with opioid overdose: a nationwide analysis.

ABSTRACT:

Background

The opioid crisis continues to affect communities across the US, with significant sex- and race-based disparities in outcomes. Limited research has explored how these disparities influence hospitalization outcomes after opioid overdose.

Methods

We conducted a retrospective cohort study using the National Inpatient Sample database. Opioid overdose codes specific to opioid poisoning were used. We analyzed in-hospital outcomes including mortality, complications, and healthcare utilization across sex and racial groups.

Results

Among 479,175 hospitalizations for opioid overdose, males accounted for 52% and had higher mortality than females (adjusted odds ratio [aOR], 1.13; 95% confidence interval [CI], 1.09-1.17; P < 0.001). Mortality declined over time f

SUBMITTER: Quazi MA 

PROVIDER: S-EPMC12671507 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature