Influence of Comorbidity on Endovascular Thrombectomy Outcomes for Medium-Vessel Occlusion Stroke: A Nationwide Prospective Observational Study.

ABSTRACT:

Background

Comorbidity burden may affect the outcome following endovascular thrombectomy (EVT) for medium-vessel occlusions. Since patients with high comorbidity burden are likely to be underrepresented in trials on EVT for medium-vessel occlusions, observational data are needed to assess the benefit of EVT for these patients.

Methods

We conducted an observational study on all prestroke independent patients treated with EVT for medium-vessel occlusions in the MCA territory in Sweden from 2015 to 2021. Comorbidity burden was weighted according to the Charlson Comorbidity Index (CCI) and categorized into no comorbidity (CCI 0); moderate to severe comorbidity (CCI 1-2); and very severe comorbidity (CCI ≥3). The primary outcome was a favorable outcome (modified Rankin Scale 0-2)

SUBMITTER: Hall E 

PROVIDER: S-EPMC12671622 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature