Effect of simplified exercise program on quality of life, biomarkers, pain and muscle strength of individuals with knee osteoarthritis.

ABSTRACT:

Objective

To evaluate a simplified exercise program for patients with knee osteoarthritis in terms of pain, functionality, muscle strength, and quality of life. The correlation of serum levels of molecules and cytokines was evaluated after the exercise program.

Methods

Overall, 47 patients with knee osteoarthritis participated in this single-arm interventional study. Outcomes were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index, Quality of Life, Visual Analog Scale, Timed Up and Go functional test, and muscle strength assessment. Serum levels of molecules and cytokines were analyzed using enzyme-linked immunosorbent assays.

Results

The program resulted in improvements in pain and physical function (0.21 points; 95%CI=-0.26; -0.17), Vi

SUBMITTER: Campedelli RR 

PROVIDER: S-EPMC12671636 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature