Role of thyroid autoimmunity independent of thyroid hormone levels in pulmonary function decline: A population-based study in euthyroid adults.

ABSTRACT:

Purpose

Although overt thyroid dysfunction has been associated with changes in pulmonary function, the effects of thyroid hormone levels and thyroid autoimmunity on lung function in euthyroid individuals remain unclear. We investigated the associations between subtle changes in thyroid hormones and thyroid peroxidase antibodies (TPOAb) and pulmonary function in a nationally representative cohort of Korean adults.

Methods

We analyzed data from 2,626 euthyroid participants aged ≥ 40 years from the Korea National Health and Nutrition Examination Survey (2013-2015). Pulmonary function was assessed using spirometry-derived forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and FEV1/FVC ratio. Multivariable linear regression analyses were conducted after adj

SUBMITTER: Sung KH 

PROVIDER: S-EPMC12671791 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature