Emphysema elevates the DETECT scores: impact on pulmonary hypertension screening and diagnosis in systemic sclerosis.

ABSTRACT:

Objectives

Combined pulmonary fibrosis and emphysema (CPFE) predicts unfavourable outcomes in systemic sclerosis (SSc). CPFE and emphysema are associated with pulmonary function tests (PFTs) abnormalities. As screening algorithms for pulmonary hypertension include PFTs, we aimed to assess whether CPFE and emphysema affect the performance of the DETECT algorithm to select patients for right-heart catheterization (RHC).

Methods

SSc patients from our referral centre, with available chest tomography images to identify emphysema or interstitial lung disease (ILD) and data to calculate the DETECT score were included. Baseline visit was set as the first visit with available information. Patients with any form of pulmonary hypertension at baseline were excluded. We tested the associ

SUBMITTER: Sauer GM 

PROVIDER: S-EPMC12671872 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature