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Added value of ophthalmic artery Doppler in prediction of pre-eclampsia: systematic review and meta-analysis.


ABSTRACT:

Objectives

Pre-eclampsia (PE) is a multisystem pregnancy-specific disorder, and its screening remains a global health priority. The primary goals of this systematic review and meta-analysis were to accumulate all available data to assess the potential added value of maternal ophthalmic artery (OA) Doppler indices in combination with several established biophysical markers for the prediction of preterm and term PE, and to update the current knowledge regarding the clinical relevance of this biophysical marker.

Methods

This systematic review and meta-analysis was designed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. MEDLINE, Scopus, ClinicalTrials.gov, EMBASE, Cochrane Central Register of Controlled Trials and Google

SUBMITTER: Sapantzoglou I 

PROVIDER: S-EPMC12671936 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature