Optimizing blood pressure control in multimorbid hypertensive patients: insights from a real-world taiwanese cohort.

ABSTRACT:

Objective

Guidelines from ACC/AHA, ESC/ESH, and JNC 8 recommend ACE inhibitors (ACEi), ARBs, calcium channel blockers (CCBs), and diuretics for hypertension in patients with cardiometabolic multimorbidity (CMM). Their effectiveness in Asians is underexplored. This study evaluates their association with mortality in Taiwanese patients with hypertension and CMM.

Methods

A population-based cohort study was conducted using Taiwan's administrative health databases (2004-2014). Patients aged ≥20 years with hypertension and ≥8 outpatient blood pressure measurements were included. All-cause mortality was assessed using inverse probability weighted Cox models, evaluating medication classes, adherence, and systolic blood pressure (SBP) control.

Results

Of 80 748 patients (mean

SUBMITTER: Sum SK 

PROVIDER: S-EPMC12672040 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature