Hypersensitive C-reactive protein-atherogenic index as a novel marker for metabolic dysfunction-associated steatotic liver disease in type 2 diabetes mellitus.

ABSTRACT:

Background

Hypersensitive C-reactive protein-atherogenic index (CAI) may serve as a novel marker for metabolic dysfunction-associated steatotic liver disease (MASLD) in type 2 diabetes mellitus (T2DM). This study aimed to evaluate the association between CAI and MASLD risk, while comparing its diagnostic performance with C-reactive protein-triglyceride glucose index (CTI), triglyceride-glucose (TyG) index, and atherogenic index of plasma (AIP).

Method

The final cohort included 1,071 individuals with T2DM from the Metabolic Management Center of our hospital. The association between CAI and MASLD was assessed by the binomial logistic regression, restricted cubic splines (RCS), and subgroup analysis. Receiver operating characteristic curve analysis was performed to evaluate the

SUBMITTER: Wang W 

PROVIDER: S-EPMC12672254 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature