Associations of specific food sources of dietary fat with prostate cancer incidence and mortality: results from a large prospective cohort.

ABSTRACT:

Background

Although fat intake has been implicated in prostate cancer (PCa) risk, the specific impact of dietary fat from specific food sources on PCa susceptibility in United States populations remains unclear.

Methods

This prospective cohort included 49,424 men from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Cox proportional hazards regression was used to evaluate the risk of PCa incidence and mortality. Subgroup and sensitivity analyses were performed to investigate the potential effect modifiers.

Results

During follow-up, we documented 4,308 incident cases of PCa, of whom 392 died from PCa. Total amount and specific types of fat intakes were not associated with PCa incidence and mortality. When considering available food sources, a greater

SUBMITTER: Fu YX 

PROVIDER: S-EPMC12672308 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature