Less invasive surfactant administration versus intubation-surfactant-extubation: a single-center retrospective study.

ABSTRACT:

Background

In recent years, minimally invasive methods have been increasingly utilized for surfactant administration in spontaneously breathing preterm infants with respiratory distress syndrome (RDS) managed with nasal continuous positive airway pressure owing to their feasibility and association with improved respiratory outcomes. However, data are limited from developing countries on the use and effectiveness of these techniques.

Purpose

The primary objective of this study was to evaluate the effect of less invasive surfactant administration (LISA) and intubation-surfactant-extubation (InSurE) techniques on the need for intubation and invasive mechanical ventilation (MV) within 72 hours of surfactant administration in preterm neonates with RDS. The secondary objectives we

SUBMITTER: Jithin CS 

PROVIDER: S-EPMC12672400 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature