Comparative analysis of ultrasound-guided magnetic resonance imaging-cognitive fusion transrectal versus transperineal prostate biopsy: a 10-year single-center retrospective analysis.

ABSTRACT:

Objectives

Prostate cancer (PCa) remains a leading malignancy among men worldwide. The diagnostic approach, particularly the biopsy route and integration with imaging, is crucial for accuracy. This study aimed to directly compare the diagnostic efficacy and safety of two ultrasound-guided, MRI-cognitively fused prostate biopsy approaches using a consistent extended 12 + X-core sampling scheme: the transperineal (TPB) versus the transrectal (TRB) route.

Methods

We conducted a comparative, retrospective analysis of 3,208 patients who underwent prostate biopsy at our institution between January 2015 and January 2024. Patients were categorized into two cohorts: a historical TRB cohort (n = 1,078) from 2015-2018 and a subsequent TPB cohort (n = 2,130) from 2018-2024

SUBMITTER: Luo J 

PROVIDER: S-EPMC12672434 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature