Development and validation of an epidemiological risk score for neonatal death in a middle-income country.

ABSTRACT:

Introduction

Despite global reductions in neonatal mortality, significant disparities remain between regions and population groups. Identifying newborns at higher risk at birth may help direct preventive actions and enhance health planning.

Objective

To develop an epidemiological risk score for neonatal death based on individual and contextual factors.

Methods

A cohort study was conducted using data from over 5.6 million live births in 645 municipalities of São Paulo State, Brazil, between 2009 and 2018. The outcome was neonatal death. Risk weights were calculated from adjusted odds ratios obtained through multilevel logistic regression, with coefficients transformed using the natural logarithm and scaled from 1 to 10. Internal validation was performed within the coho

SUBMITTER: Areco KN 

PROVIDER: S-EPMC12672502 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature