The GBD 2021 perspective: COVID-19's impact on diarrheal mortality and etiological trends, 1990-2021.

ABSTRACT:

Introduction

Diarrheal diseases remain a leading cause of global mortality. While significant progress has been made in reducing diarrheal deaths, particularly among children under five, the COVID-19 pandemic introduced new dynamics through non-pharmaceutical interventions and healthcare disruptions. Understanding the evolving burden during this period is critical for guiding post-pandemic control strategies.

Methods

Using data from the Global Burden of Disease Study 2021, we analyzed diarrhea-related deaths and age-standardized death rates (ASDRs) across 204 countries from 1990 to 2021. Estimated annual percentage changes (EAPCs) were calculated to assess temporal trends. Analyses were stratified by age, sex, socio-demographic index (SDI), and 13 major diarrheal pathogens.<

SUBMITTER: Sang S 

PROVIDER: S-EPMC12672554 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature