Initial local treatment strategies on survival outcomes of early-stage breast mucosa-associated lymphoid tissue lymphoma.

ABSTRACT: To compare survival outcomes among different initial treatment strategies for early-stage (stage I-II) breast mucosa-associated lymphoid tissue (MALT) lymphoma. Using data from the Surveillance, Epidemiology, and End Results program, we analyzed patients diagnosed with early-stage breast MALT lymphoma between 2000 and 2017. Statistical analyses included chi-square tests, Kaplan-Meier survival estimates, and multivariate Cox proportional-hazards models. Among 396 eligible patients, treatment strategies included surgery with or without postoperative radiotherapy (161 patients, 40.7%), radiotherapy alone (122 patients, 30.8%), and observation (113 patients, 28.5%). Temporal trends indicated increasing use of radiotherapy alone, while surgery alone and observation declined (P = 0.061). With a

SUBMITTER: Chen HY 

PROVIDER: S-EPMC12672607 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature