Shift work and metabolic dysfunction-associated steatotic liver disease: a systematic review of observational studies.

ABSTRACT:

Objective

Shift work disrupts the circadian rhythm and may increase the risk of metabolic disorders, including nonalcoholic fatty liver disease, recently redefined as metabolic dysfunction-associated steatotic liver disease (MASLD), and its progressive form, metabolic dysfunction-associated steatohepatitis. This systematic review aimed to synthesize observational studies on the association between shift work and MASLD.

Methods

A comprehensive literature search was conducted in the PubMed, Scopus, and Web of Science databases up to November 25, 2024, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data were extracted and summarized based on pre-specified inclusion and exclusion criteria. The National Institutes of Health quality as

SUBMITTER: Ma B 

PROVIDER: S-EPMC12672679 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature