Socioeconomic vulnerability and osteoporosis treatment disparities during COVID-19 lockdown among U.S. medicare enrollees who initiated romosozumab.

ABSTRACT: Higher area socioeconomic level was associated with a decreased risk of romosozumab discontinuation during COVID-19 lockdown among U.S. Medicare beneficiaries. Patients in these areas were more likely to restart osteoporosis treatment post-discontinuation. Timely support for vulnerable patients is crucial for improving adherence during public health crises.

Purpose

To evaluate the association between area socioeconomic (SES) vulnerability and the discontinuation of romosozumab and the impact of the COVID lockdown on osteoporosis treatment among women enrolled in the U.S. Medicare who initiated romosozumab.

Methods

Female Medicare beneficiaries aged 65 and older who initiated romosozumab between April 2019 and September 2020 were included. Discontinuation was defined as a > 60

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12672750 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature