Effects of physical exercise in patients undergoing haematopoietic stem cell transplantation: systematic review and meta-analysis.

ABSTRACT:

Purpose

To evaluate the effects of physical exercise on key clinical outcomes (such as quality of life (QoL), aerobic capacity, fatigue, and muscle strength) in patients undergoing haematopoietic stem cell transplantation.

Methods

PRISMA systematic review and meta-analysis from inception to April 2025. PubMed, Embase, Cochrane Library, Web of Science and Scopus databases were searched for eligible studies. Methodological quality and risk of bias were evaluated with the Pedro scale and the Risk-Of-Bias Tool for randomized trials (ROB2.0) respectively.

Results

An initial search retrieved 5217 articles. Finally, 20 studies were included in the qualitative synthesis and 7 in the meta-analysis. Exercise showed a small, non-significant effect on QoL (SMD = 0.23; p = 0.072),

SUBMITTER: Martin-Sanchez C 

PROVIDER: S-EPMC12672829 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature