Outcomes and Healthcare Resource Utilisation in Adults With von Willebrand Disease Receiving On-Demand Recombinant von Willebrand Factor in the United Kingdom.

ABSTRACT:

Objectives

We describe treatment outcomes and healthcare resource utilisation (HCRU) in adults with von Willebrand disease (VWD) treated on demand with recombinant von Willebrand factor (rVWF) in the United Kingdom.

Methods

Retrospective chart review of adults (≥ 18 years) with congenital VWD receiving first-time rVWF for the on-demand treatment of spontaneous/traumatic bleeds, or the prevention/treatment of surgical bleeds, between 1 October 2020 and 30 June 2022 at seven hospitals. Treatment, outcome and VWD-related HCRU data associated with the on-demand treatment of all recorded bleeds were collected at first (index) treatment, for 12 months pre-index and 3-12 months post-index.

Results

Twelve patients (91.7% female and White/Caucasian, mean age 34.2 years) were t

SUBMITTER: Laffan M 

PROVIDER: S-EPMC12673354 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature