Seven-Day vs Four-Day Infusion Set Replacement Interval and Catheter-Related Infections.

ABSTRACT:

Importance

Catheter-related bloodstream infections (CRBSIs) are associated with longer hospital stays and increased mortality risks. The Replacement at Standard vs Prolonged Interval (RSVP) trial found that central venous access devices and peripheral arterial catheter infusion set replacement intervals can be extended from 4 to 7 days without increasing infection risk by more than 2%. However, the trial did not consider the full cost and health trade-offs of extending replacement intervals.

Objective

To estimate the changes in total cost and health benefits associated with a decision to adopt 7-day vs standard 4-day replacement intervals via decision-analytic modeling.

Design, setting, and participants

In this economic evaluation, a decision tree model was developed

SUBMITTER: Elangovan S 

PROVIDER: S-EPMC12673407 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature