The outcome of injured cervical spinal cord with uncontrolled swelling under duraplasty: protocol of the ISCUD randomized controlled trial.

ABSTRACT:

Background

Cervical traumatic spinal cord injuries (TSCIs) are the most prevalent type of traumatic spinal cord injury, marked by high disability rates, considerable medical expenses, and a poor prognosis for functional recovery. The clinical effectiveness of bony decompression in improving functional outcomes following TSCI remains limited, even when performed ultra-early (within 12 or 8 h), emphasizing the uncertainty and insufficient understanding of the extent of adequate decompression. The ISCUD trial aims (1) to evaluate the benefits and risks of combining expansive duroplasty with standard treatment compared to standard treatment alone; (2) to investigate whether spinal cord perfusion status, assessed by indocyanine green, is related to the development of spinal cord swellin

SUBMITTER: Li YC 

PROVIDER: S-EPMC12673702 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature