Probiotic ice cream influences gut and vaginal microbiota in women at high risk of preterm birth: a randomized controlled study.

ABSTRACT:

Background

Research into probiotic use in pregnancy typically focuses on general probiotic strains. We instead investigated the relation between intake of ice cream with vaginal commensal probiotics (L. crispatus, L. gasseri, L. jensenii, L. rhamnosus GR-1; these may govern a stable microbiota and may carry beneficial functions in the vagina), throughout pregnancy, and the impact on gut and vaginal microbiomes, in women at high risk of preterm birth.

Methods

This was a randomised controlled feasibility trial where the impact on gut and vaginal microbiomes was assessed by using 16 S rRNA gene sequencing and qPCR. In total 43 pregnant women were randomized, with 29 assigned to the intervention group and 14 to the control group. Both groups provided vaginal and rectal swabs by

SUBMITTER: Borum LS 

PROVIDER: S-EPMC12673775 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature