Protective effects of salvianolic acid A on ischemic stroke: A meta-analysis of preclinical studies.

ABSTRACT:

Objective

The aim of this study was to investigate the protective effects of salvianolic acid A (SalA) on cerebral ischemic injury following ischemic stroke (IS) and its possible mechanisms, providing a scientific basis for future clinical research on IS.

Methods

A comprehensive search was conducted across eight databases: PubMed, Embase, Web of Science, the Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, VIP Database, and the China Biomedical Literature Database (CBM). The search included all literature from the establishment of each library up to February 2025. Data analysis was performed using STATA 15.0 software.

Results

A total of 15 studies involving 564 animals were included. The analysis showed that compared to the control g

SUBMITTER: Liu A 

PROVIDER: S-EPMC12673838 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature