Risk factors for calcification in chronic pancreatitis: a systematic review and meta-analysis.

ABSTRACT:

Background/objectives

Pancreatic calcifications are the most common structural change in chronic pancreatitis (CP). They can be associated with increased morbidity and healthcare costs. The factors associated with calcifying CP phenotype are not fully understood. Therefore, we aimed to investigate risk factors for calcification in patients with CP.

Methods

The study protocol was registered in PROSPERO(CRD42024591837). On September 18, 2024, we systematically searched three databases (PubMed, EMBASE, and CENTRAL) for studies reporting factors associated with calcifications in CP. Pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated using a random-effects model.

Results

The systematic search resulted in 10,893 articles, of which 80 eligible studies

SUBMITTER: Eperjesi O 

PROVIDER: S-EPMC12673887 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature