Safety of long-term creatine supplementation in women's football players: a real-world in-season study.

ABSTRACT: Although creatine supplementation is well established for enhancing athletic performance, data on its long-term safety are still limited, particularly among female athletes. This study investigated the effects of in-season creatine supplementation on biochemical safety markers in young female football players. This real-world, longitudinal single-arm study assessed the safety of creatine supplementation during a competitive season in 71 female athletes from youth and professional football teams. Participants received 20 g/day of creatine monohydrate for 7 days, followed by 5 g/day for the remainder of the season. Dietary intake and a comprehensive panel of hematological, renal, and hepatic biomarkers were evaluated at baseline, mid- (week 16), and end-season (week 32). Linear mixed-model w

SUBMITTER: Garcia MP 

PROVIDER: S-EPMC12673977 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature