High-frequency hearing loss in chronic kidney disease: a frequency-specific analysis across renal function stages.

ABSTRACT: Chronic kidney disease (CKD) has been associated with a wide range of neurological complications, yet the onset and pattern of hearing loss, particularly at high frequencies, remain insufficiently characterized. This study aimed to evaluate hearing function across different stages of renal impairment with a focus on frequency-specific thresholds. A total of 97 participants were retrospectively assessed and divided into three groups: preserved estimated glomerular filtration rate (eGFR) (n = 32), CKD without hemodialysis (n = 32), and patients undergoing hemodialysis (n = 33). Pure-tone audiometry was performed to assess both conventional and high-frequency hearing thresholds. Comparative analyses using Kruskal-Wallis and Mann-Whitney U-tests were conducted. Patients wi

SUBMITTER: Sahin MF 

PROVIDER: S-EPMC12673979 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature