Identification of SNPs in the second intron of <i>IGF2BP1</i> and their Association with growth traits in Nanjiang Yellow goat.

ABSTRACT: Insulin-like Growth Factor 2 mRNA-binding Protein 1 (IGF2BP1) is a candidate gene of significant interest for modulating economically important traits in livestock and poultry. The second intron of IGF2BP1 has been implicated in growth-related traits, though its precise mechanistic role remains elusive. Initial resequencing analyses in our laboratory indicated strong selective pressures on the IGF2BP1 genomic region, prompting the selection and identification of several single nucleotide polymorphisms (SNPs). Seven SNPs were mapped to the conserved region of the second intron, necessitating further investigation into their functional relevance and association with growth traits. In this study, 348 Nanjiang Yellow goats were analyzed, and the association analysis via th

SUBMITTER: Chen S 

PROVIDER: S-EPMC12674248 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature