Methylome and transcriptome joint analyses identify differentially expressed genes based on purebred and crossbred Tianjin-monkey Chicken.

ABSTRACT: Tianjin-monkey Chicken is a locally bred naked neck poultry with limited population size. Herein, we intended to identify potential breed-related genes based on methylome and transcriptome analyses. Tianjin-monkey Chicken and Hy-line Brown Chicken were crossbred and the individuals were divided into three groups: PN (Purebred naked neck chicken(Tianjin-monkey Chicken)) group (n = 10); CN (Crossbred naked neck chicken) group (n = 10); CF (Crossbred feathered chicken) group (n = 10). These 30 individuals were subjected to whole genome bisulfite sequencing (WGBS) and transcriptome sequencing. Differential methylated regions were detected by WGBS. No significant difference existed in naked-neck-related traits between PN and CN chicken. CpG methylation level of the promoter region differed in P

SUBMITTER: Xia S 

PROVIDER: S-EPMC12674283 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature